What the Harvard researches did was create mice with a controllable

What the Harvard researches did was create mice with a controllable telomerase gene, which resulted in a batch of prematurely aged rodents. Their short, dysfunctional telomeres resulted in the sort of muscle and brain deterioration often seen in the elderly, as well as humans with premature aging disorders.Rather than supply the rodents with supplemental telomerase, the scientists devised a way to switch on the animals' own replica Breitling A4435910/B811 Men's watch dormant telomerase gene, known as TERT. They engineered the endogenous TERT gene to encode a fusion protein of TERT and the estrogen receptor. This fusion protein would only become activated with a special form of estrogen. With this setup, scientists could give the mice an estrogen-like drug at any time to stimulate the TERT-estrogen receptor fusion protein and make it active to maintain telomeres.

One group of mice had a time-release estrogen pill implanted under their skin. The other did not.

After four weeks, the estrogen-treated mice showed amazing rejuvenation. The telomerase gene was working anew, creating healthy-sized telomeres. Tissue that was degenerating weeks before was now growing once more. The spleen and brain showed increased size. The animals regained their sense of smell, lost due to premature aging. heir brains replica Breitling A4935011/C671 Men's watch began to produce new neurons. And yes, the testes were more powerful than ever.”One of the most amazing changes was in the animals' testes, which were essentially barren as aging caused the death and elimination of sperm cells,” recounted DePinho. “When we restored telomerase, the testes produced new sperm cells, and the animals' fecundity was improved - their mates gave birth to larger litters.”

The animals did not live longer than their untreated counterparts, but it certainly sounds like they lived better.So what does this all mean to humans? The possibility of effectively reversing age-related diseases could change the way the world ages. The rest home industry could suffer and Wal-Mart might run out of greeters, but that's a small replica Breitling Windrider Cockpit Men's Watch price to pay for a more graceful aging process, and who doesn't want more powerful testes?Partial reversal of aging achieved in mice [Physorg]”Video game creator Sion Lenton had an idea for one level of his next war video game. The sequence would feature Marines, probably in near-future Tajikistan, on assignment, on patrol. They'd walk around, looking for bad guys. They'd find none.